MINICD4 MICROBICIDE PREVENTS HIV INFECTION OF HUMAN MUCOSAL EXPLANTS AND VAGINAL TRANSMISSION OF SHIV(162P3) IN CYNOMOLGUS MACAQUES.

MiniCD4 microbicide prevents HIV infection of human mucosal explants and vaginal transmission of SHIV(162P3) in cynomolgus macaques.

In complement to an effective vaccine, development of potent anti-HIV microbicides remains an important priority.We have previously shown that the miniCD4 M48U1, a functional mimetic of sCD4 Hockey Protective - Shoulder Pads - Youth presented on a 27 amino-acid stable scaffold, inhibits a broad range of HIV-1 isolates at sub-nanomolar concentration

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Towards the Task-Level Optimal Orchestration Mechanism in Multi-Device Multi-Task Architecture for Mission-Critical IoT Applications

Internet of Things is advancing, and the augmented role of architecture in automating processes is at its vanguard.Mission-critical applications are becoming a vital category of future IoT applications, and due to the advancements in the 5G, the design of mission-critical application overcome a big hurdle.Mission-critical applications must be relia

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Scenario-based land use management to restore natural areas and reducing soil erosion rate in a competing land uses condition

Identifying the Sleep Support contribution of different land uses plays a crucial role in preventing erosion and prioritizing land management activities.This research aimed to assess the impacts of various land use scenarios on mitigating soil erosion in the North West Urmia region of Iran.In addition to the current scenario, 12 land use management

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